CD209 Recombinant antibody, PBS Only

CD209 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

240907A2

Cat no : 84095-6-PBS

Synonyms

DC SIGN1, DC SIGN, C-type lectin domain family 4 member L, CLEC4L, CDSIGN

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Validation Data Gallery

• 

  WB analysis of human placenta using 84095-6-RR (same clone as 84095-6-PBS)

  human placenta tissue was subjected to SDS PAGE followed by western blot with 84095-6-RR (CD209 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84095-6-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 84095-6-RR

  Biolayer interferometry (BLl) kinetic assays of 84095-6-RR against Human CD209 were performed. The affinity constant is below 1 pM.

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Product Information

The immunogen of 84095-6-PBS is CD209 Fusion Protein expressed in E. coli.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Fusion Protein
• Full Name: CD209 molecule
• Calculated Molecular Weight: 404 aa, 45.7 kDa
• Observed Molecular Weight: 48 kDa
• GenBank Accession Number: BC110615
• Gene Symbol: CD209
• Gene ID (NCBI): 30835
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).