BSAP,PAX5 Monoclonal antibody, PBS Only
BSAP,PAX5 Monoclonal Antibody for WB, FC, IHC, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
WB, FC, IHC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2H2D6
Cat no : 60349-1-PBS
Synonyms
Validation Data Gallery
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
60349-1-PBS targets BSAP,PAX5 in WB, FC, IHC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | BSAP,PAX5 fusion protein Ag16023 |
Full Name | paired box 5 |
Calculated Molecular Weight | 391 aa, 42 kDa |
Observed Molecular Weight | 42 kDa |
GenBank Accession Number | BC156927 |
Gene Symbol | PAX5 |
Gene ID (NCBI) | 5079 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
PAX5, also named B-cell specific activator protein (BSAP), is a member of the highly conserved paired box (PAX)-domain family of transcription factors. PAX5 is essential in normal B-cell lymphopoiesis. It is expressed in pro-B, pre-B and mature B lymphocytes but not in plasma cells. PAX5 is a common target in leukemogenesis of B-ALL ( B-lineage acute lymphoblastic leukemia) along with CDKN2A. Owing to its frequent deletion in B-ALL, PAX5 could be used as one of the molecular markers in diagnosis and monitoring of the disease. This antibody is specific to PAX5. It will not cross react with other PAX members.