BCR Monoclonal antibody, PBS Only
BCR Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
Human, rat
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2C2E3
Cat no : 67260-1-PBS
Synonyms
Validation Data Gallery
Product Information
67260-1-PBS targets BCR in WB, Indirect ELISA applications and shows reactivity with Human, rat samples.
Tested Reactivity | Human, rat |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | BCR fusion protein Ag28953 |
Full Name | breakpoint cluster region |
Calculated Molecular Weight | 143 kDa |
Observed Molecular Weight | 150-160 kDa |
GenBank Accession Number | BC066122 |
Gene Symbol | BCR |
Gene ID (NCBI) | 613 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
The Bcr gene, mapping on chromosome22, was orginally identified by its presence in the chimeric Bcr-Abl oncogene. The Bcr gene encodes for the break point cluster region protein(Bcr). Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for RAC1 and CDC42. A chromosomal aberration involving BCR has been found in patients with chronic myeloid leukemia.