CoraLite® Plus 488-conjugated AMH Polyclonal antibody

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• KD/KO Validated

AMH Polyclonal Antibody for IF-P

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF-P

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-14461

Synonyms

AMH, anti Mullerian hormone, MIF, MIS

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Validation Data Gallery

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  IF Staining of mouse ovary using CL488-14461

  Immunofluorescent analysis of (4% PFA) fixed mouse ovary tissue using CoraLite® Plus 488 AMH antibody (CL488-14461) at dilution of 1:200.

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  IF Staining of mouse ovary using CL488-14461

  Immunofluorescent analysis of (4% PFA) fixed mouse ovary tissue using CoraLite® Plus 488 AMH antibody (CL488-14461) at dilution of 1:200.

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Tested Applications

• Positive IF-P detected in: mouse ovary tissue

Recommended dilution

• Immunofluorescence (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

CL488-14461 targets AMH in IF-P applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: AMH fusion protein Ag5670
• Full Name: anti-Mullerian hormone
• Calculated Molecular Weight: 59 kDa
• GenBank Accession Number: BC049194
• Gene Symbol: AMH
• Gene ID (NCBI): 268
• Conjugate: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 493 nm / 522 nm
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
• Storage Conditions: Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Background Information

Anti-Müllerian hormone (AMH), also called Müllerian-inhibiting substance (MIS), is a hormone that is best known for its production by fetal testes in mammals and as the inhibitor of Müllerian duct development in males. AMH is also expressed in granulosa cells of preantral and small antral follicles in the ovary. More recently, AMH has been studied for its role in ovarian folliculogenesis and as a potential marker of ovarian reserve. The deduced protein sequence of the AMH monomer contains a 25 amino acid secretion specific signal peptide and a monomeric protein of 535 amino acids that, when glycosylated at two glycosylation sites, has a molecular weight of 65-70 kDa. This antibody is specific to AMH.