CoraLite®594-conjugated AGR2 Monoclonal antibody
AGR2 Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG2b
Reactivity
Human, Pig
Applications
IF/ICC
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
1A8A8
Cat no : CL594-66768
Synonyms
Validation Data Gallery
Tested Applications
Positive IF/ICC detected in | HT-29 cells |
Recommended dilution
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
CL594-66768 targets AGR2 in IF/ICC applications and shows reactivity with Human, Pig samples.
Tested Reactivity | Human, Pig |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | AGR2 fusion protein Ag2919 |
Full Name | anterior gradient homolog 2 (Xenopus laevis) |
Calculated Molecular Weight | 175 aa, 20 kDa |
Observed Molecular Weight | 17 kDa |
GenBank Accession Number | BC015503 |
Gene Symbol | AGR2 |
Gene ID (NCBI) | 10551 |
RRID | AB_2920033 |
Conjugate | CoraLite®594 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. |
Background Information
AGR2, also named AG2 or HPC8, encodes anterior gradient protein 2 homolog which belongs to the AGR family. It is a secreted protein localized in endoplasmic reticulum. AGR2 plays roles in MUC2 post-transcriptional synthesis,secretion and production of mucus by intestinal cells. AGR2 was significantly elevated in the pancreatic juice from patients with pre-malignant conditions as well as pancreatic cancer compared to control pancreatic juice samples. AGR2 levels in pancreatic juice could potentially be used to aide in assessment of high-risk patients undergoing endoscopic procedures.
Protocols
Product Specific Protocols | |
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IF protocol for CL594 AGR2 antibody CL594-66768 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |