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p38 MAPK Monoclonal antibody, PBS Only (Capture)
p38 MAPK Monoclonal Antibody for WB, IHC, Cytometric bead array, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human, mouse, rat, pig
Applications
WB, IHC, Cytometric bead array, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1A1C2
Cat no : 66234-1-PBS
Synonyms
Validation Data Gallery
Product Information
66234-1-PBS targets p38 MAPK as part of a matched antibody pair:
MP50419-1: 66234-1-PBS capture and 68965-1-PBS detection (validated in Cytometric bead array)
MP50419-2: 66234-1-PBS capture and 68966-1-PBS detection (validated in Cytometric bead array)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
Tested Reactivity | human, mouse, rat, pig |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | p38 MAPK fusion protein Ag5797 |
Full Name | mitogen-activated protein kinase 14 |
Calculated Molecular Weight | 360 aa, 41 kDa |
Observed Molecular Weight | 38-42 kDa |
GenBank Accession Number | BC031574 |
Gene Symbol | p38 MAPK |
Gene ID (NCBI) | 1432 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cell self-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.