Anticorps Polyclonal de lapin anti-PROX1

• Phare
• Validé par KD/KO

PROX1 Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris et plus (1)

Applications

WB, IHC, IF, CoIP, ChIP,ELISA

Conjugaison

Non conjugué

Publications

10

N° de cat : 51043-1-AP

Synonymes

prospero homeobox 1, Prospero homeobox protein 1, PROX 1, PROX1

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Galerie de données de validation

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  WB analysis of rat brain using 51043-1-AP

  rat brain tissue were subjected to SDS PAGE followed by western blot with 51043-1-AP (PROX1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of human brain using 51043-1-AP

  human brain tissue were subjected to SDS PAGE followed by western blot with 51043-1-AP (PROX1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  IHC staining of human lymphoma using 51043-1-AP

  Immunohistochemical analysis of paraffin-embedded human lymphoma using 51043-1-AP (PROX1 antibody) at dilution of 1:50 (under 10x lens).

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Applications testées

Dilution recommandée

Application	Dilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 3 publications below
• WB: See 5 publications below
• IHC: See 2 publications below
• IF: See 2 publications below
• CoIP: See 2 publications below
• ChIP: See 2 publications below

Informations sur le produit

51043-1-AP cible PROX1 dans les applications de WB, IHC, IF, CoIP, ChIP,ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: Humain, souris, Hamster
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PROX1 Protéine recombinante Ag0457
• Nom complet: prospero homeobox 1
• Masse moléculaire calculée: 737 aa, 83 kDa
• Poids moléculaire observé: 90 kDa
• Numéro d’acquisition GenBank: BC024201
• Symbole du gène: PROX1
• Identification du gène (NCBI): 5629
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20 ℃. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

PROX1, Prospero homeobox protein 1, belongs to the Prospero homeobox family and contain a Prospero-type homeobox DNA-binding domain. PROX1 plays a fundamental role in early development of CNS and regulated the expression of gene and development of postmitotic undifferentiated young neuron. Also PROX1 is a specific and required regulator of the development of the lymphatic system. This is a rabbit polyclonal antibody raised against part of C-terminal chain of human PROX1.

Publications

Species	Application	Title
human,mouse	WB,CoIP,ChIP	Genes Dev; The homeobox protein Prox1 is a negative modulator of ERR{alpha}/PGC-1{alpha} bioenergetic functions.; Authors - Charest-Marcotte Alexis A ; KD Validated
mouse	CoIP,chIP	Nat Commun; An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides.; Authors - Sean M Armour
human	WB	PLoS Genet; Genomic convergence among ERRα, PROX1, and BMAL1 in the control of metabolic clock outputs.; Authors - Dufour Catherine R CR ; KD Validated
human	WB	Nucleic Acids Res; Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors α- and γ-mediated transactivation.; Authors - Takeda Yukimasa Y ; KD Validated
human	IHC,IF	Am J Pathol; Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation.; Authors - Jie-Gang Yang
human	IHC	PLoS One; Impact of an Altered PROX1 Expression on Clinicopathology, Prognosis and Progression in Renal Cell Carcinoma.; Authors - Tao Lv

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