SFTPC Polyklonaler Antikörper

SFTPC Polyklonal Antikörper für WB, IHC, IF-P, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte und mehr (1)

Anwendung

WB, IHC, IF-P, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10774-1-AP

Synonyme

SP5, SP C, SMDP2, SFTP2, Pulmonary surfactant-associated proteolipid SPL(Val)



Geprüfte Anwendungen

Erfolgreiche Detektion in WBMauslungengewebe, Rattenlungengewebe
Erfolgreiche Detektion in IHChumanes Lungengewebe
Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.
Erfolgreiche Detektion in IF-PMauslungengewebe

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:500-1:2000
Immunhistochemie (IHC)IHC : 1:500-1:2000
Immunfluoreszenz (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

10774-1-AP bindet in WB, IHC, IF-P, ELISA SFTPC und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
In Publikationen genannte Reaktivitäthuman, Hausschwein, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SFTPC fusion protein Ag1159
Vollständiger Name surfactant protein C
Berechnetes Molekulargewicht 21 kDa
Beobachtetes Molekulargewicht 21-25 kDa
GenBank-ZugangsnummerBC005913
Gene symbol SFTPC
Gene ID (NCBI) 6440
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SFTPC (surfactant protein C), also named as SFTP2, SP5 and SP-C, is a pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. Defects in SFTPC are the cause of pulmonary surfactant metabolism dysfunction type 2 (SMDP2). Genetic variations in SFTPC are associated with respiratory distress syndrome in premature infants (RDS). Two isoforms of the human protein are produced by alternative splicing. One previous study reported that SFTPC deletion was observed in NSCLC tissues, implying that SFTPC downregulation might be involved in the progression of lung cancer. (PMID: 35081981, PMID: 31379200)

Protokolle

Produktspezifische Protokolle
WB protocol for SFTPC antibody 10774-1-APProtokoll herunterladen
IHC protocol for SFTPC antibody 10774-1-APProtokoll herunterladen
IF protocol for SFTPC antibody 10774-1-APProtokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
pigWB,IF

Sci Total Environ

Protein lysine acetylation played an important role in NH3-induced AEC2 damage and pulmonary fibrosis in piglets

Authors - Xiaotong Wang
humanIHC

Theranostics

A SCID mouse-human lung xenograft model of SARS-CoV-2 infection.

Authors - Wenkun Fu
mouseIF

Oncogene

HAO1-mediated oxalate metabolism promotes lung pre-metastatic niche formation by inducing neutrophil extracellular traps.

Authors - Zhicheng Zeng
mouseWB,IF

Int J Mol Sci

Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway.

Authors - Guangying Yang
human,mouseIHC

J Pathol

Overexpression of the SARS-CoV-2 receptor ACE2 is induced by cigarette smoke in bronchial and alveolar epithelia.

Authors - Aibin Liu
mouseWB,IF

iScience

Tat-P combined with GAPR1 releases Beclin1 to promote autophagy and improve Bronchopulmonary dysplasia model

Authors - Yahui Zhou

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

David (Verified Customer) (03-29-2022)

ICC on ALIs without antigen retrieval.

  • Applications: Immunofluorescence
  • Primary Antibody Dilution: 1:100
  • Cell Tissue Type: Primary alveolar type 2 cells