• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human IL-15 protein


0.07-0.37 ng/mL for NK-92 bioassay.

Specific Activity

minimally 3.50 x 107 IU/mg

Species Reactivity




Cat no : HZ-1323


Interleukin 15, IL15, IL-15MGC9721, Interleukin-15

Technical Specifications

GeneID 3600
Species Human
Expression HEK293
Activity(Primary) 0.07-0.37 ng/mL for NK-92 bioassay.
Activity(Secondary)3-17 ng/mL for MO7e Bioassay
Specific Activityminimally 3.50 x 107 IU/mg
Purity >95%
Endotoxin<1 EU/µg
Accession NumberP40933
Molecular Mass 12 to 24 kDa reduced, 11 to 23 kDa non-reduced, monomer, glycosylated
Formulation 50 mM Acetate pH 4.0 + 150mM NaCl
Species Reactivity human,mouse,rat

Stability and Reconstitution

Stability and StorageProduct FormTemperature ConditionsStorage Time
(From Date of Receipt)
Lyophilized-20°C to -80°CUntil Expiry Date
LyophilizedRoom Temperature2 weeks
Reconstituted as per CofA-20°C to -80°C6 months
Reconstituted as per CofA4°C1 week
Avoid repeated freeze-thaw cycles.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein to 0.2 mg/mL in sterile 1x PBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA). Gently swirl or tap vial to mix.


IL-15 is a 4-α-helix bundle cytokine playing a pivotal role in stimulation of both innate and adaptive immune cells. It is produced primarily by keratinocytes, skeletal muscle cells, monocytes, and CD4+ T cells. It is a member of the common gamma chain family. The members of the common gamma chain family include the IL-2, IL-4, IL-7, IL-9, and IL-21 and require binding to the common  chain receptor for activation. It can be used in growth and maintenance of T and NK cells. It is also shown to be used in proliferation and functional effect of T cells for adoptive cell therapy. It is a glycosylated protein and HumanKine IL-15 appear as 12.5-25 kDa bands (PMID: 24587813, 26627006, 27849617, 31250350)


Interleukin 15, IL15, IL-15MGC9721, Interleukin-15



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