• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human IL-15 protein- GMP grade


0.07-0.37 ng/mL EC50 for NK-92 Bioassay.

Specific Activity

>4.00 x 107 IU/mg

Species Reactivity




ISO 13485 certified HumanKine® human cell-expressed cytokines and growth factors

Cat no : HZ-1323-GMP


Interleukin 15, IL15, IL-15MGC9721, Interleukin-15

Technical Specifications

GeneID 3600
Species Human
Expression HEK293
EC50 0.07-0.37 ng/mL EC50 for NK-92 Bioassay.
Activity(Secondary)3-17 ng/mL EC50 for MO7e Bioassay.
Specific Activity>4.00 x 107 IU/mg
Purity >95%
Endotoxin< 0.1 EU/µg
Accession NumberP40933
Molecular Mass 11-23 kDa
Formulation 50 mM Acetate pH 4.0 + 150mM NaCl
Species Reactivity human

Stability and Reconstitution

Stability and StorageProduct FormTemperature ConditionsStorage Time
(From Date of Receipt)
Lyophilized-20°C to -80°CUntil Expiry Date
LyophilizedRoom Temperature2 weeks
Reconstituted as per CofA-20°C to -80°C6 months
Reconstituted as per CofA4°C1 week
Avoid repeated freeze-thaw cycles.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1x PBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA).

GMP Quality Policies

HumanKine® GMP (Good Manufacturing Practice) recombinant proteins are manufactured and validated in accordance with ISO 13485 quality management system and is compliant with GMP.
Our GMP recombinant proteins are animal component free (ACF), xeno free (XF) and tag free (TF). Read more about these policies here.


IL-15 is a 4-α-helix bundle cytokine playing a pivotal role in stimulation of both innate and adaptive immune cells. It is produced primarily by keratinocytes, skeletal muscle cells, monocytes, and CD4+ T cells. It is a member of the common gamma chain family. The members of the common gamma chain family include the IL-2, IL-4, IL-7, IL-9, and IL-21 and require binding to the common  chain receptor for activation. It can be used in growth and maintenance of T and NK cells. It is also shown to be used in proliferation and functional effect of T cells for adoptive cell therapy. It is a glycosylated protein and HumanKine IL-15 appear as 12.5-25 kDa bands (PMID: 24587813, 26627006, 27849617, 31250350).


Interleukin 15, IL15, IL-15MGC9721, Interleukin-15