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c-Cbl Monoclonal antibody, PBS Only

c-Cbl Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 66576-1-PBS
Clone No.2F6D1

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, IHC, Indirect ELISA

C CBL, CBL, CBL2, c-Cbl, Proto oncogene c Cbl, RING finger protein 55, RNF55

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

66576-1-PBS targets c-Cbl in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen c-Cbl fusion protein Ag23033 Predict reactive species
Full Name Cas-Br-M (murine) ecotropic retroviral transforming sequence
Calculated Molecular Weight 906 aa, 100 kDa
Observed Molecular Weight 100-120 kDa
GenBank Accession NumberBC132733
Gene Symbol CBL
Gene ID (NCBI) 867
RRIDAB_2881936
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP22681
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

c-Cbl (Casitas B-lineage lymphoma) is a critical regulator that controls immature or follicular helper T cell development, B cell development, immune tolerance, angiogenesis, or tumorigenesis (PMID: 33962939). c-Cbl also plays a pivotal role in regulating dendritic cell (DC) function via negatively modulating IL-12 production after Toll-like receptor (TLR) stimulation (PMID: 21799517).

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