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ZnT3 Polyclonal antibody, PBS Only

ZnT3 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17363-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using ZnT3 Polyclonal antibody (17363-1-AP)

    WB analysis using 17363-1-AP (same clone as 17363-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17363-1-AP (ZnT3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17363-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human brain tissue using ZnT3 Polyclonal antibody (17363-1-AP)

    IHC staining of human brain using 17363-1-AP (same clone as 17363-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain using 17363-1-AP (ZnT3 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17363-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human brain tissue using ZnT3 Polyclonal antibody (17363-1-AP)

    IHC staining of human brain using 17363-1-AP (same clone as 17363-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain using 17363-1-AP (ZnT3 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17363-1-PBS in a different storage buffer formulation.

Product Information

17363-1-PBS targets ZnT3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ZnT3 fusion protein Ag10735
Full Name solute carrier family 30 (zinc transporter), member 3
Calculated Molecular Weight 388 aa, 42 kDa
Observed Molecular Weight 42 kDa, 48 kDa
GenBank Accession NumberBC028358
Gene Symbol ZnT3
Gene ID (NCBI) 7781
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

ZnT3, encoded by SLC30A3, is a member of SLC30A family which is zinc transporter sequestrating cytosolic zinc into intracellular compartments or effluxing zinc to the extracellular space. Excessive zinc level can cause neuron apoptosis and lead to cognitive impairments. Znt3 facilitates the transport and storage of zinc in synaptic vesicles. Abnormal ZnT3 expression has been linked to some neurodegenerative disorders.