Zinc Alpha 2 Glycoprotein Monoclonal antibody, PBS Only

Zinc Alpha 2 Glycoprotein Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

4B8A4

Cat no : 66178-1-PBS

Synonyms

AZGP1, ZA2G, ZAG, Zinc alpha 2 glycoprotein, Zinc-alpha-2-glycoprotein, Zn alpha 2 glycoprotein, Zn alpha 2 GP, ZNGP1

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Validation Data Gallery

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  WB analysis of human plasma using 66178-1-Ig (same clone as 66178-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 66178-1-Ig (AZGP1 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66178-1-Ig (AZGP1 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66178-1-Ig (AZGP1 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate hyperplasia using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate hyperplasia tissue slide using 66178-1-Ig (AZGP1 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate cancer using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 66178-1-Ig (AZGP1 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate cancer using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 66178-1-Ig (AZGP1 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate hyperplasia using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate hyperplasia tissue slide using 66178-1-Ig (AZGP1 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

• 

  IF Staining of human breast cancer using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human breast cancer tissue using Zinc Alpha 2 Glycoprotein antibody (66178-1-Ig, Clone: 4B8A4 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

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Product Information

66178-1-PBS targets Zinc Alpha 2 Glycoprotein in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: Zinc Alpha 2 Glycoprotein fusion protein Ag5661
• Full Name: alpha-2-glycoprotein 1, zinc-binding
• Calculated Molecular Weight: 298 aa, 34 kDa
• Observed Molecular Weight: 41 kDa
• GenBank Accession Number: BC033830
• Gene Symbol: Zinc Alpha 2 Glycoprotein
• Gene ID (NCBI): 563
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Zinc-alpha-2-glycoprotein (AZGP1), a 41-kDa soluble protein normally found in body fluids, functions as a lipid mobilizing factor (PMID: 19188554). It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract, and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex (MHC) antigens (PMID: 3422450). AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors (PMID: 22625427).