YY2 Monoclonal antibody, PBS Only

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  WB analysis of human kidney using 66839-1-Ig (same clone as 66839-1-PBS)

  human kidney tissue were subjected to SDS PAGE followed by western blot with 66839-1-Ig (YY2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66839-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human placenta using 66839-1-Ig (same clone as 66839-1-PBS)

  human placenta tissue were subjected to SDS PAGE followed by western blot with 66839-1-Ig (YY2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66839-1-PBS in a different storage buffer formulation.

• 

  WB analysis of MCF-7 using 66839-1-Ig (same clone as 66839-1-PBS)

  MCF-7 cells were subjected to SDS PAGE followed by western blot with 66839-1-Ig (YY2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66839-1-PBS in a different storage buffer formulation.

YY2 Monoclonal Antibody for WB, ELISA

Cat No. 66839-1-PBS

Clone No.1C11A7

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, ELISA

Synonyms

Transcription factor YY2, Yin and yang 2, YY 2, YY2, YY2 transcription factor, Zinc finger protein 631, ZNF631

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Product Information

66839-1-PBS targets YY2 in WB, ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: YY2 fusion protein Ag25373
• Full Name: YY2 transcription factor
• Calculated Molecular Weight: 372 aa, 46 kDa
• Observed Molecular Weight: 46 kDa
• GenBank Accession Number: BC137217
• Gene Symbol: YY2
• Gene ID (NCBI): 404281
• RRID: AB_2882182
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: O15391
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

YY2 (Yin-Yang 2) encodes a zinc finger transcription factor similarity to the well-characterized YY1 that locating to nucleus. Both proteins recognize an identical DNA-binding motifs with a high homologous Zinc Finger region, and these transcription factors can act as activators or repressors when bound to DNA (PMID:26350623). It is reported that YY2 is placental mammal-specific and is absent in marsupial and non-mammalian vertebrate species (PMID:16377127). YYs are play an important role in multiple developmental processes , such as implantation, cell differentiation, X inactivation, imprinting and organogenesis (PMID:27191592). YY2 is expressed in kindey, liver, spleen and testicle but not in the colon (PMID:15087442). A 41kDa band could be detected.