Mouse VEGFA Recombinant antibody, PBS Only

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  IF Staining of NIH/3T3 using 82864-7-RR (same clone as 82864-7-PBS)

  Immunofluorescent analysis of (4% PFA) fixed NIH/3T3 cells using Vegfa antibody (82864-7-RR, Clone: 2I18 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 82864-7-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 82864-7-RR

  Biolayer interferometry (BLl) kinetic assays of 82864-7-RR against Mouse Vegfa were performed. The affinity constant is below 1 pM.

VEGFA {ptg:Brand} Recombinant Antibody for IF/ICC, Indirect ELISA

Cat No. 82864-7-PBS

Clone No.2I18

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

IF/ICC, Indirect ELISA

Synonyms

Vascular endothelial growth factor A, long form, vascular endothelial growth factor A, Vascular Endothelial Growth Factor, N-VEGF, L-VEGF

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Product Information

82864-7-PBS targets VEGFA in IF/ICC, Indirect ELISA applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: vascular endothelial growth factor A
• GenBank Accession Number: NM_001287056
• Gene Symbol: Vegfa
• Gene ID (NCBI): 22339
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

Vegfa is a member of the PDGF/VEGF growth factor family. It is a mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, endothelial cell growth, promoting cell migration, and inhibiting apoptosis.It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. It may play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis.