Anti-Human VISTA Rabbit Recombinant Antibody, PBS Only

VISTA Uni-rAb^TM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241003C8

Cat no : 98109-1-PBS

Synonyms

C10orf54, SISP1, PP2135, GI24, B7-H5

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Validation Data Gallery

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  FC experiment of human peripheral blood leukocytes using 98109-1-RR (same clone as 98109-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human VISTA Rabbit Recombinant Antibody (98109-1-RR, Clone:241003C8) (red) or Isotype Control (blue) and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98109-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human peripheral blood leukocytes using 98109-1-RR (same clone as 98109-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human VISTA Rabbit Recombinant Antibody (98109-1-RR, Clone:241003C8) or Isotype Control and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98109-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 98109-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98109-1-RR against Human VISTA were performed. The affinity constant is 0.933 nM.

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Product Information

The immunogen of 98109-1-PBS is VISTA Fusion Protein expressed in E. coli.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Fusion Protein
• Full Name: chromosome 10 open reading frame 54
• Calculated Molecular Weight: 311 aa, 34 kDa
• GenBank Accession Number: BC020568
• Gene Symbol: VISTA
• Gene ID (NCBI): 64115
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

VISTA, also known as platelet receptor Gi24, B7-H5, C10orf54, Dies1, PD-1H, and SISP1, is a member of the immunoglobulin superfamily. It serves not only as a positive regulator but also as a substrate of MT1-MMP and contributes at least in part to tumor invasion.