CoraLite® Plus 488-conjugated Uteroglobin/CC10 Polyclonal antibody

Uteroglobin/CC10 Polyclonal Antibody for IF-P

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IF-P

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-10490

Synonyms

SCGB1A1, Uteroglobin, Club cells 10 kDa secretory protein, Club cell phospholipid-binding protein, CCSP

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Validation Data Gallery

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  IF Staining of mouse lung using CL488-10490

  Immunofluorescent analysis of (4% PFA) fixed mouse lung tissue using CoraLite® Plus 488 Uteroglobin/CC10 antibody (CL488-10490) at dilution of 1:200.

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  IF Staining of mouse lung using CL488-10490

  Immunofluorescent analysis of (4% PFA) fixed mouse lung tissue using CoraLite® Plus 488 Uteroglobin/CC10 antibody (CL488-10490) at dilution of 1:200.

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Tested Applications

• Positive IF-P detected in: mouse lung tissue

Recommended dilution

• Immunofluorescence (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

CL488-10490 targets Uteroglobin/CC10 in IF-P applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Uteroglobin/CC10 fusion protein Ag0758
• Full Name: secretoglobin, family 1A, member 1 (uteroglobin)
• Calculated Molecular Weight: 10 kDa
• GenBank Accession Number: BC004481
• Gene Symbol: Uteroglobin
• Gene ID (NCBI): 7356
• Conjugate: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 493 nm / 522 nm
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
• Storage Conditions: Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Background Information

Uteroglobin, also known as CC10, is a member of the secretoglobin family of small secreted proteins. It is produced by the nonciliated, nonmucous, secretory epithelial clara cells of the pulmonary airways, was first identified in lung lavage by Singh and colleagues. It has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.