UCP2 Monoclonal antibody, PBS Only

UCP2 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 66700-1-PBS
Clone No.2B4B1

Host / Isotype

Mouse / IgG3

Reactivity

Human

Applications

WB, Indirect ELISA

BMIQ4, SLC25A8, UCP 2, UCP2, UCPH

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


It is strongly recommended that fresh-made lysate be used for western blot assays.

Product Information

66700-1-PBS targets UCP2 in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG3
Class Monoclonal
Type Antibody
Immunogen UCP2 fusion protein Ag19361 Predict reactive species
Full Name uncoupling protein 2 (mitochondrial, proton carrier)
Calculated Molecular Weight 33 kDa
Observed Molecular Weight 28 kDa
GenBank Accession NumberBC011737
Gene Symbol UCP2
Gene ID (NCBI) 7351
RRIDAB_2882053
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP55851
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

UCP2 (uncoupling protein 2) is a member of the mitochondrial carrier protein super family located in the mitochondrial inner membrane. The UCPs differ greatly in tissue distribution: UCP1 is expressed only in brown adipose; UCP3 preferentially in skeletal muscle, brown adipose and heart; UCP4 and UCP5 mainly in the nervous system (18167556). In contract, UCP2 has a broad distribution and is implicated in a wide range of pathophysiological processes, including diabetes and cancer. This antibody detect a band around 28-33 kDa corresponding to UCP2 protein in mouse liver, skeletal muscle and pancreas. Some upper and lower bands also were observed due to the dimer formation and degradation of the UCP2 protein (20103532). This antibody was raised against the full-length UCP2 protein and may cross-react with UCP3. It is notable that UCP2 is known to have a very short half-life less than 1 hour (17240372). It is strongly recommended that fresh-made lysate be used for western blot assays.

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