Product Information
68565-1-PBS targets UBR2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | UBR2 fusion protein Ag13446 Predict reactive species |
Full Name | ubiquitin protein ligase E3 component n-recognin 2 |
Calculated Molecular Weight | 439aa,50 kDa; 1755aa,201 kDa |
Observed Molecular Weight | 201 kDa |
GenBank Accession Number | BC064512 |
Gene Symbol | UBR2 |
Gene ID (NCBI) | 23304 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q8IWV8 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
UBR2(Ubiquitin-protein ligase E3-alpha-2) is also named as C6orf133, KIAA0349 and N-recognin-2. It is a component of the N-end rule pathway and recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. It has four isoforms produced by alternative splicing.