Product Information
81854-1-PBS targets UBE2S in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | UBE2S fusion protein Ag5264 Predict reactive species |
Full Name | ubiquitin-conjugating enzyme E2S |
Calculated Molecular Weight | 222 aa, 24 kDa |
Observed Molecular Weight | 28 kDa |
GenBank Accession Number | BC066948 |
Gene Symbol | UBE2S |
Gene ID (NCBI) | 27338 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q16763 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
UBE2S(Ubiquitin-conjugating enzyme E2 S) is also named as E2EPF and belongs to the ubiquitin-conjugating enzyme family. It acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C) and a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Overexpression of UBE2S can increase tumor cell proliferation, invasion, and metastasis through the VHL-HIF pathway (PMID:16819549).