TOX2 Monoclonal antibody, PBS Only

TOX2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat, rabbit

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2G12A7

Cat no : 68590-1-PBS

Synonyms

C20orf100, dJ1108D11.2, dJ495O3.1, GCX 1, GCX1, TOX2

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Validation Data Gallery

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  WB analysis using 68590-1-Ig (same clone as 68590-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68590-1-Ig (TOX2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 68590-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68590-1-Ig (same clone as 68590-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68590-1-Ig (TOX2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 68590-1-PBS in a different storage buffer formulation.

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Product Information

68590-1-PBS targets TOX2 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, rabbit samples.

• Tested Reactivity: Human, mouse, rat, rabbit
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: TOX2 fusion protein Ag31563
• Full Name: TOX high mobility group box family member 2
• Calculated Molecular Weight: 52KD
• Observed Molecular Weight: 70 kDa
• GenBank Accession Number: NM_001098797
• Gene Symbol: TOX2
• Gene ID (NCBI): 84969
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

TOX2 is a transcription factor belonging to the TOX (thymocyte selection-associated HMG box) family that shares a highly conserved high mobility group DNA-binding domain with the other TOX members. A previous study showed that TOX2 is preferentially expressed in human NK cells among various leukocyte populations and is required for in vitro and in vivo human NK cell differentiation from UCB-derived CD341 hematopoietic stem cells (HSCs) (PMID: 25352127).