CoraLite® Plus 647-conjugated TINAGL1 Polyclonal antibody

• Featured Product
• KD/KO Validated

TINAGL1 Polyclonal Antibody for IF

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF-P

Conjugate

CoraLite® Plus 647 Fluorescent Dye

Cat no : CL647-12077

Synonyms

ARG1, GIS5, LCN7, LIECG3, OLRG 2, OLRG2, PSEC0088, TIN Ag related protein, TIN Ag RP, TINAGL, TINAGL1, TINAGRP, UNQ204/PRO230

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Validation Data Gallery

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  IF Staining of human liver cancer using CL647-12077

  Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite® Plus 647 TINAGL1 antibody (CL647-12077) at dilution of 1:200.

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  IF Staining of human liver cancer using CL647-12077

  Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite® Plus 647 TINAGL1 antibody (CL647-12077) at dilution of 1:200.

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Tested Applications

• Positive IF-P detected in: human liver cancer tissue

Recommended dilution

• Immunofluorescence (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

CL647-12077 targets TINAGL1 in IF-P applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: TINAGL1 fusion protein Ag2721
• Full Name: tubulointerstitial nephritis antigen-like 1
• Calculated Molecular Weight: 467 aa, 52 kDa
• Observed Molecular Weight: 52 kDa
• GenBank Accession Number: BC009048
• Gene Symbol: TINAGL1
• Gene ID (NCBI): 64129
• RRID: AB_2920220
• Conjugate: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 654 nm / 674 nm
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
• Storage Conditions: Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20^oC storage.

Background Information

Tinagl1 (tubulointer stitial nephritis antigen-like 1) is a matricellular protein most commonly associated with embryonic development, including the heart and adrenal glands. Low levels of Tinagl1 expression can be dire for craniofacial development and for female fertility. Tinagl1 can bind to EGFR and integrins on TNBC cells using the 4T1 murine model and that by interrupting normal tumor signaling in this way, cancer proliferation and metastasis pathways were downregulated.