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  • Featured Product
  • KD/KO Validated

TEAD2 Polyclonal antibody, PBS Only

TEAD2 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 21159-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of mouse colon tissue using TEAD2 Polyclonal antibody (21159-1-AP)

    WB analysis of mouse colon using 21159-1-AP (same clone as 21159-1-PBS)

    mouse colon tissue were subjected to SDS PAGE followed by western blot with 21159-1-AP (TEAD2 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21159-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse lung tissue using TEAD2 Polyclonal antibody (21159-1-AP)

    WB analysis of mouse lung using 21159-1-AP (same clone as 21159-1-PBS)

    mouse lung tissue were subjected to SDS PAGE followed by western blot with 21159-1-AP (TEAD2 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21159-1-PBS in a different storage buffer formulation.

Product Information

21159-1-PBS targets TEAD2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TEAD2 fusion protein Ag14074
Full Name TEA domain family member 2
Calculated Molecular Weight 447 aa, 49 kDa
Observed Molecular Weight 55-65 kDa
GenBank Accession NumberBC051301
Gene Symbol TEAD2
Gene ID (NCBI) 8463
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

TEAD2 belongs to a protein family that shares the TEA/ATTS domain. It acts as a transcriptional factor by cooperatively binding to the GT-IIC and Sph(I 1 II) enhansons in the simian virus 40 (SV40) enhancer. Also, it can modulate SV40 late transcription together with a large T antigen. The transcriptional activity of TEAD2 required several regions of the proteins, TBP-associated factors, and limiting transcriptional intermediary factors. TEAD2 also performs an essential role in the Hippo signaling pathway. TEAD2 regulates gene expression of YAP1 and WWTR1/TAZ, thus mediating cell proliferation, migration, and epithelial-mesenchymal transition induction. TEAD2 is strongly expressed in the human ovarian carcinoma cell line.