TAX1BP1 Monoclonal antibody, PBS Only

TAX1BP1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1H2D10

Cat no : 60466-1-PBS

Synonyms

TRAF6-binding protein, Tax1-binding protein 1, T6BP, PRO0105, 1H2D10

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Validation Data Gallery

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  WB analysis using 60466-1-Ig (same clone as 60466-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60466-1-Ig (TAX1BP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60466-1-PBS in a different storage buffer formulation.

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Product Information

60466-1-PBS targets TAX1BP1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: TAX1BP1 fusion protein Ag6279
• Full Name: Tax1 (human T-cell leukemia virus type I) binding protein 1
• Calculated Molecular Weight: 91 kDa
• Observed Molecular Weight: 68 kDa, 85 kDa
• GenBank Accession Number: BC050358
• Gene Symbol: TAX1BP1
• Gene ID (NCBI): 8887
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms, this antibody recognizes both TXBP151-L and TXBP151-S.