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TAX1BP1 Monoclonal antibody

TAX1BP1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1H2D10

Cat no : 60466-1-Ig

Synonyms

TRAF6-binding protein, Tax1-binding protein 1, T6BP, PRO0105, 1H2D10

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using TAX1BP1 Monoclonal antibody (60466-1-Ig)

    WB analysis using 60466-1-Ig

    Various lysates were subjected to SDS PAGE followed by western blot with 60466-1-Ig (TAX1BP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

Tested Applications

Positive WB detected inA549 cells, U2OS cells, HeLa cells, HepG2 cells, Jurkat cells, K-562 cells, HSC-T6 cells, NIH/3T3 cells, 4T1 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

60466-1-Ig targets TAX1BP1 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen TAX1BP1 fusion protein Ag6279
Full Name Tax1 (human T-cell leukemia virus type I) binding protein 1
Calculated Molecular Weight 91 kDa
Observed Molecular Weight68 kDa, 85 kDa
GenBank Accession NumberBC050358
Gene Symbol TAX1BP1
Gene ID (NCBI) 8887
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms, this antibody recognizes both TXBP151-L and TXBP151-S.

Protocols

Product Specific Protocols
WB protocol for TAX1BP1 antibody 60466-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols