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TAB2 Recombinant antibody, PBS Only

TAB2 Uni-rAbTM Recombinant Antibody for Indirect ELISA, WB

Host / Isotype

Rabbit / IgG

Reactivity

mouse, human

Applications

Indirect ELISA, WB

Conjugate

Unconjugated

CloneNo.

230118F1

Cat no : 82948-5-PBS

Synonyms

MAP3K7IP2, TAB-2, TAB 2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, KIAA0733

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using TAB2 Recombinant antibody (82948-5-RR)

    WB analysis using 82948-5-RR (same clone as 82948-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82948-5-RR (MAP3K7IP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82948-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82948-5-RR

    Affinity and Kinetic Characterization of 82948-5-RR

    Biolayer interferometry (BLl) kinetic assays of 82948-5-RR against Human TAB2 were performed. The affinity constant is 65.2 pM.

Product Information

82948-5-PBS targets TAB2 in Indirect ELISA, WB applications and shows reactivity with mouse, human samples.

Tested Reactivity mouse, human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen TAB2 fusion protein Ag5742
Full Name mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Calculated Molecular Weight 76 kDa
Observed Molecular Weight77 kDa
GenBank Accession NumberBC035910
Gene Symbol MAP3K7IP2
Gene ID (NCBI) 23118
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Tab2 has a role in the inflammatory signal transduction pathway and is involved in the reversal of NCoR-dependent and NFkB- or APP-mediated gene repression and androgen antagonist response. Besides, it is identified as a cofactor for ERBB4 to assemble NCoR corepressor complex in response to neuregulin [PMID:16469706]. It also functions as an adaptor that links TAK1 and TRAF6 in response to interleukin-1β (IL-1β) or tumour necrosis factor-α (TNF-α), and thereby mediates TAK1 activation [PMID:11460167].