SYNGR1 Recombinant antibody, PBS Only

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  WB analysis using 84161-3-RR (same clone as 84161-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84161-3-RR (SYNGR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84161-3-PBS in a different storage buffer formulation.

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  WB analysis of pig brain using 84161-3-RR (same clone as 84161-3-PBS)

  pig brain tissue was subjected to SDS PAGE followed by western blot with 84161-3-RR (SYNGR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84161-3-PBS in a different storage buffer formulation.

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  IF Staining of mouse brain using 84161-3-RR (same clone as 84161-3-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using SYNGR1 antibody (84161-3-RR, Clone: 241460D1 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84161-3-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84161-3-RR

  Biolayer interferometry (BLl) kinetic assays of 84161-3-RR against Human SYNGR1 were performed. The affinity constant is 3.48 nM.

SYNGR1 {ptg:Brand} Recombinant Antibody for WB, IF-P, Indirect ELISA

Cat No. 84161-3-PBS

Clone No.241460D1

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat, pig

Applications

WB, IF-P, Indirect ELISA

Synonyms

Synaptogyrin-1, synaptogyrin 1, 241460D1

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Product Information

84161-3-PBS targets SYNGR1 in WB, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.

• Tested Reactivity: human, mouse, rat, pig
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: SYNGR1 fusion protein Ag0685
• Full Name: synaptogyrin 1
• Calculated Molecular Weight: 25 kDa
• Observed Molecular Weight: 30 kDa
• GenBank Accession Number: BC000731
• Gene Symbol: SYNGR1
• Gene ID (NCBI): 9145
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: O43759
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

Synaptogyrins are one of the most abundant vesicle components and are involved in the regulation of neurotransmitter release and synaptic plasticity. Synaptogyrins comprise a family of tyrosine-phosphorylated proteins with three isoforms: two neuronal forms (synaptogyrin-1 and -3) and one ubiquitous form (synaptogyrin-2). The synaptogyrin 1 (SYNGR1) can act as a regulator of Ca2+-dependent exocytosis. SYNGR1 protein mutations are associated with schizophrenia and are considered to be positional candidate genes for schizophrenia.(PMID: 10383386; 10595519; 14755516; 14732601; 17049558)