STXBP1 Monoclonal antibody, PBS Only
STXBP1 Monoclonal Antibody for WB, IHC, IF-P, FC (Intra), Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human, mouse, rat, pig
Applications
WB, IHC, IF-P, FC (Intra), Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1B5B3
Cat no : 67137-1-PBS
Synonyms
Validation Data Gallery
Product Information
67137-1-PBS targets STXBP1 in WB, IHC, IF-P, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.
Tested Reactivity | human, mouse, rat, pig |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | STXBP1 fusion protein Ag28605 |
Full Name | syntaxin binding protein 1 |
Calculated Molecular Weight | 594 aa, 68 kDa |
Observed Molecular Weight | 68 kDa |
GenBank Accession Number | BC015749 |
Gene Symbol | STXBP1 |
Gene ID (NCBI) | 6812 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
STXBP1, also named as UNC18A, N-Sec1 and p67 belongs to the STXBP/unc-18/SEC1 family. STXBP1 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. It is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. STXBP1 can interact with syntaxins 1, 2, and 3 but not syntaxin 4. It may play a role in determining the specificity of intracellular fusion reactions.