CoraLite® Plus 488-conjugated STOML2 Polyclonal antibody

• Featured Product
• KD/KO Validated

STOML2 Polyclonal Antibody for IF/ICC

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-10348

Synonyms

SLP2, SLP 2, Paratarg-7, Paraprotein target 7, EPB72-like protein 2

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Validation Data Gallery

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  IF Staining of HeLa using CL488-10348

  Immunofluorescent analysis of (4% PFA) fixed HeLa cells using CoraLite® Plus 488 STOML2 antibody (CL488-10348) at dilution of 1:200, CL594-Phalloidin (red).

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  IF Staining of HeLa using CL488-10348

  Immunofluorescent analysis of (4% PFA) fixed HeLa cells using CoraLite® Plus 488 STOML2 antibody (CL488-10348) at dilution of 1:200.

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Tested Applications

• Positive IF/ICC detected in: HeLa cells

Recommended dilution

• Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

CL488-10348 targets STOML2 in IF/ICC applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: STOML2 fusion protein Ag0363
• Full Name: stomatin (EPB72)-like 2
• Calculated Molecular Weight: 356 aa, 39 kDa
• Observed Molecular Weight: 39 kDa
• GenBank Accession Number: BC002442
• Gene Symbol: STOML2
• Gene ID (NCBI): 30968
• Conjugate: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 493 nm / 522 nm
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
• Storage Conditions: Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Background Information

STOML2 (Stomatin-like protein 2; also known as SLP-2) is a widely expressed mitochondrial member of the highly conserved family of stomatin proteins. STOML2 is localized mostly in mitochondrial inner membrane, minor in plasma membrane. Human STOML2 interacts with prohibitins and regulates mitochondrial biogenesis and function (21746876). In addition, plenty of studies revealed that STOML2 was overexpressed in many human cancer tissues, and its expression may be a new valuable prognostic biomarker (19839737, 21960069). Recently STOML2 has been identified as a serological biomarker for early colorectal cancer (CRC) diagnosis (21209152). Two isoforms of STOML2 exist due to the alternative splicing, with MW of 39 kDa and 33 kDa, respectively.