Product Information
67204-1-PBS targets STMN2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.
Tested Reactivity | human, mouse, rat, pig |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | STMN2 fusion protein Ag28990 Predict reactive species |
Full Name | stathmin-like 2 |
Calculated Molecular Weight | 21 kDa |
Observed Molecular Weight | 22 kDa |
GenBank Accession Number | BC006302 |
Gene Symbol | STMN2 |
Gene ID (NCBI) | 11075 |
RRID | AB_2882497 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q93045 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
STMN2 gene encodes a SCG10 (superior cervical ganglion-10) protein, a regulator of microtubule stability. When phosphorylated by MAPK8, SCG10 stabilizes microtubules and consequently controls neurite length in cortical neurons. SCG10 was early considered a neuron-specific growth-associated protein in Alzheimer's disease. In the developing brain, SCG10 negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone.