STK24 Monoclonal antibody, PBS Only

STK24 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2B4C1

Cat no : 68522-1-PBS

Synonyms

MST 3, MST3, MST3B, STE20, STE20 like kinase MST3, STK24, STK3

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Validation Data Gallery

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  WB analysis using 68522-1-Ig (same clone as 68522-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68522-1-Ig (STK24 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68522-1-PBS in a different storage buffer formulation.

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Product Information

68522-1-PBS targets STK24 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

• Tested Reactivity: Human, mouse, rat
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: STK24 fusion protein Ag31526
• Full Name: serine/threonine kinase 24 (STE20 homolog, yeast)
• Calculated Molecular Weight: 49KD
• Observed Molecular Weight: 50 kDa
• GenBank Accession Number: NM_003576
• Gene Symbol: STK24
• Gene ID (NCBI): 8428
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Serine/threonine-protein kinase 24 (STK24), also named MST3, belonging to GCK subfamily of STE20-like kinases, acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation (PubMed: 10644707, PMID:12107159). STK24 and STK25 operate in the same cardiovascular development pathway with programmed cell death 10 (CCM3) (PMID: 20332113). It regulates axon outgrowth in forebrain neurons (PubMed: 17114295).