SPATA7 Polyclonal antibody, PBS Only

• 

  WB analysis using 12020-1-AP (same clone as 12020-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12020-1-AP (SPATA7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12020-1-PBS in a different storage buffer formulation.

• 

  IP experiment of mouse testis using 12020-1-AP (same clone as 12020-1-PBS)

  IP result of anti-SPATA7 (IP:12020-1-AP, 3ug; Detection:12020-1-AP 1:300) with mouse testis tissue lysate 8000ug. This data was developed using the same antibody clone with 12020-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

SPATA7 Polyclonal Antibody for WB, IP, Indirect ELISA

Cat No. 12020-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, Indirect ELISA

Synonyms

---

Product Information

12020-1-PBS targets SPATA7 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SPATA7 fusion protein Ag2649
• Full Name: spermatogenesis associated 7
• Calculated Molecular Weight: 599 aa, 68 kDa
• Observed Molecular Weight: 68-80 kDa
• GenBank Accession Number: BC008656
• Gene Symbol: SPATA7
• Gene ID (NCBI): 55812
• RRID: AB_2195380
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9P0W8
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

SPATA7, also named as HSD3, may be involved in retinal function. It is interesting to note that mutations in SPATA7 cause LCA and RP/ARRP , two overlapping but distinct human retinal diseases. SPATA7 is another LCA and Juvenile RP Gene.(PMID:19268277) It is a highly conserved, vertebrate-specific protein which expressed in the mature retina. For some modification, the MW always migrate 5-8kd. The antibody can reoginze all the 3 isoforms of SPATA7.