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  • Featured Product
  • KD/KO Validated

SPATA7 Polyclonal antibody, PBS Only

SPATA7 Polyclonal Antibody for WB, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 12020-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using SPATA7 Polyclonal antibody (12020-1-AP)

    WB analysis using 12020-1-AP (same clone as 12020-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 12020-1-AP (SPATA7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12020-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of mouse testis tissue using SPATA7 Polyclonal antibody (12020-1-AP)

    IP experiment of mouse testis using 12020-1-AP (same clone as 12020-1-PBS)

    IP result of anti-SPATA7 (IP:12020-1-AP, 3ug; Detection:12020-1-AP 1:300) with mouse testis tissue lysate 8000ug. This data was developed using the same antibody clone with 12020-1-PBS in a different storage buffer formulation.

Product Information

12020-1-PBS targets SPATA7 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SPATA7 fusion protein Ag2649
Full Name spermatogenesis associated 7
Calculated Molecular Weight 599 aa, 68 kDa
Observed Molecular Weight 68-80 kDa
GenBank Accession NumberBC008656
Gene Symbol SPATA7
Gene ID (NCBI) 55812
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

SPATA7, also named as HSD3, may be involved in retinal function. It is interesting to note that mutations in SPATA7 cause LCA and RP/ARRP , two overlapping but distinct human retinal diseases. SPATA7 is another LCA and Juvenile RP Gene.(PMID:19268277) It is a highly conserved, vertebrate-specific protein which expressed in the mature retina. For some modification, the MW always migrate 5-8kd. The antibody can reoginze all the 3 isoforms of SPATA7.