• Featured Product
  • KD/KO Validated

SOX9 Monoclonal antibody

SOX9 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse and More (4)

Applications

WB, IF, FC, ELISA

Conjugate

Unconjugated

CloneNo.

1H9A6

Cat no : 67439-1-Ig

Synonyms

CMD1, CMPD1, SOX9, SRA1, Transcription factor SOX 9



Tested Applications

Positive WB detected inhuman placenta tissue, Caco-2 cells, HT-29 cells, NCCIT cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Sample-dependent, check data in validation data gallery

Product Information

67439-1-Ig targets SOX9 in WB, IF, FC, ELISA applications and shows reactivity with Human, mouse samples.

Tested Reactivity Human, mouse
Cited Reactivityhuman, mouse, rat, canine, rabbits
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen SOX9 fusion protein Ag28620
Full Name SRY (sex determining region Y)-box 9
Calculated molecular weight 509 aa, 56 kDa
Observed molecular weight 56 kDa
GenBank accession numberBC007951
Gene symbol SOX9
Gene ID (NCBI) 6662
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

SOX9, also named as Transcription factor SOX-9, is a 509 amino acid protein. Sex-determining region Y (SRY)-box 9 protein (SOX9) is a member of the SOX family of transcription factors (TFs) which are developmental regulators that possess high mobility group (HMG) box DNA binding and transactivation domains. It participates in a variety of functions, such as lineage restriction and terminal diferentiation, through precise temporal and spatial expression patterns that difer between particular cell types and tissues. SOX9 gene has been implicated in different types of cancer as an oncogene; however, it also may behave as a tumor suppressor.

Protocols

Product Specific Protocols
WB protocol for SOX9 antibody 67439-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
ratWB

J Nanobiotechnology

Dual-dynamic-bond cross-linked injectable hydrogel of multifunction for intervertebral disc degeneration therapy

Authors - Linjun Yang
mouseWB

Free Radic Biol Med

Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes

Authors - Wenchao Wang
humanWB

EBioMedicine

Decreased miR-214-3p activates NF-κB pathway and aggravates osteoarthritis progression.

Authors - Yumei Cao
ratWB

Front Pharmacol

Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway

Authors - Tianwen Ma
humanFC

Commun Biol

Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells.

Authors - LinXi Cheng
canineIF

J Steroid Biochem Mol Biol

Dihydrotestosterone through blockade of TGF-β/Smad signaling mediates the anti-fibrosis effect under hypoxia in canine Sertoli cells.

Authors - Longfei Xiao