Product Information
83857-6-PBS targets SOD1 in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Recombinant protein Predict reactive species |
Full Name | superoxide dismutase 1, soluble |
Calculated Molecular Weight | 16kDa |
Observed Molecular Weight | 16-20 kDa |
GenBank Accession Number | NM_000454.5 |
Gene Symbol | SOD1 |
Gene ID (NCBI) | 6647 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P00441 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) (SOD1, synonyms: ALS, SOD, ALS1, IPOA) binds copper and zinc ions and is one of two isozymes responsible for destroying free uperoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.