SMC2 Recombinant antibody, PBS Only

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  IHC staining of mouse brain using 84835-1-RR (same clone as 84835-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84835-1-RR (SMC2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84835-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 84835-1-RR (same clone as 84835-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84835-1-RR (SMC2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84835-1-PBS in a different storage buffer formulation.

SMC2 Uni-rAb^TM Recombinant Antibody for IHC, Indirect ELISA

Cat No. 84835-1-PBS

Clone No.241536G3

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, Indirect ELISA

Synonyms

SMC protein 2, SMC 2, hCAP E, CAPE, CAP E

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Product Information

84835-1-PBS targets SMC2 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: SMC2 fusion protein Ag33471
• Full Name: structural maintenance of chromosomes 2
• Calculated Molecular Weight: 136 kDa
• GenBank Accession Number: NM_001042550.1
• Gene Symbol: SMC2
• Gene ID (NCBI): 10592
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: O95347
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (PMID: 11136719).