SLC38A7 Polyclonal antibody, PBS Only

SLC38A7 Polyclonal Antibody for IHC, IF-P, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IF-P, Indirect ELISA

Conjugate

Unconjugated

Cat no : 31486-1-PBS

Synonyms

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Validation Data Gallery

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  IHC staining of mouse brain using 31486-1-AP (same clone as 31486-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 31486-1-AP (SLC38A7 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31486-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 31486-1-AP (same clone as 31486-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 31486-1-AP (SLC38A7 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31486-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse brain using 31486-1-AP (same clone as 31486-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using SLC38A7 antibody (31486-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31486-1-PBS in a different storage buffer formulation.

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Product Information

31486-1-PBS targets SLC38A7 in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SLC38A7 fusion protein Ag35081
• Full Name: solute carrier family 38, member 7
• Calculated Molecular Weight: 50 kDa
• GenBank Accession Number: BC001961
• Gene Symbol: SLC38A7
• Gene ID (NCBI): 55238
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

SLC38A7 also known as SNAT7, is a system N transporter with a substrate preference for L-glutamine(PMID: 21511949). SLC38A7 symporter that selectively transports sodium ions and amino acids, such as L-glutamine and L-asparagine from the lysosome into the cytoplasm and may participate in mTORC1 activation (PubMed:28416685, PubMed:35561222). colocalization of Slc38a7 with neuronal markers in excitatory and inhibitory neurons, but not in astrocytes or glial cells.