SEMA7A Monoclonal antibody, PBS Only

SEMA7A Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3A5G1

Cat no : 67397-1-PBS

Synonyms

CD108, CDw108, H SEMA K1, H Sema L, JMH, JMH blood group antigen, Sema K1, Sema L, SEMA7A, SEMAK1, SEMAL, Semaphorin 7A, Semaphorin K1, Semaphorin L

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Validation Data Gallery

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  WB analysis of human red blood cells using 67397-1-Ig (same clone as 67397-1-PBS)

  human red blood cells were subjected to SDS PAGE followed by western blot with 67397-1-Ig (SEMA7A antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67397-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human placenta using 67397-1-Ig (same clone as 67397-1-PBS)

  human placenta tissue were subjected to SDS PAGE followed by western blot with 67397-1-Ig (SEMA7A antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67397-1-PBS in a different storage buffer formulation.

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Product Information

67397-1-PBS targets SEMA7A in WB, Indirect ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Mouse / IgG2b
• Class: Monoclonal
• Type: Antibody
• Immunogen: SEMA7A fusion protein Ag28804
• Full Name: semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
• Calculated Molecular Weight: 666 aa, 75 kDa
• Observed Molecular Weight: 75-80 kDa
• GenBank Accession Number: BC101643
• Gene Symbol: SEMA7A
• Gene ID (NCBI): 8482
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

SEMA7A, also named CD108 and SEMAL, belongs to the semaphorin family. SEMA7A is the only membrane‐associated glycosylphosphatidylinositol (GPI)‐linked semaphorin and plays a role in the regulation of neuronal axon outgrowth. In addition to its role in guiding axon pathfinding during neuronal development, Sema7A has diverse functions in morphogenesis and immune cell control and regulates T cell responses via the α1β1 integrin receptor (PMID: 31179640). SEMA7A has 2 isoforms with molecular weights of 73 and 75 kDa, respectively.