SEC63 Monoclonal antibody, PBS Only

SEC63 Monoclonal Antibody for WB, IF/ICC, ELISA
Cat No. 67352-1-PBS
Clone No.1C10E1

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, IF/ICC, ELISA

ERdj2, PRO2507, SEC63, SEC63 homolog (S. cerevisiae), SEC63L

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

67352-1-PBS targets SEC63 in WB, IF/ICC, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen SEC63 fusion protein Ag5783 Predict reactive species
Full Name SEC63 homolog (S. cerevisiae)
Calculated Molecular Weight 88 kDa
Observed Molecular Weight 90 kDa
GenBank Accession NumberBC047221
Gene Symbol SEC63
Gene ID (NCBI) 11231
RRIDAB_2882608
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ9UGP8
Storage Buffer PBS only
Storage ConditionsStore at -80°C.

Background Information

SEC63 is a integral ER membrane protein. SEC63 and SEC62 form a dimeric complex and play a central role in translocation of nascent and newly synthesized precursor polypeptides into the ER. Mutations in the gene encoding SEC63 cause polycystic liver disease in humans. The intact SEC63 protein is usually detected around 83-90 kDa, while smaller cleavage products can be observed by autophagy proteolysis (PMID: 25052096)

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