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RS1 Monoclonal antibody, PBS Only

RS1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, rat, mouse, rabbit

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1A2D4

Cat no : 68654-1-PBS

Synonyms

Retinoschisin, retinoschisin 1, RS, RS1, XLRS1

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using RS1 Monoclonal antibody (68654-1-Ig)

    WB analysis using 68654-1-Ig (same clone as 68654-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68654-1-Ig (RS1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68654-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse retina tissue using RS1 Monoclonal antibody (68654-1-Ig)

    WB analysis of mouse retina using 68654-1-Ig (same clone as 68654-1-PBS)

    mouse retina tissue were subjected to SDS PAGE followed by western blot with 68654-1-Ig (RS1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68654-1-PBS in a different storage buffer formulation.

Product Information

68654-1-PBS targets RS1 in WB, Indirect ELISA applications and shows reactivity with Human, rat, mouse, rabbit samples.

Tested Reactivity Human, rat, mouse, rabbit
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen RS1 fusion protein Ag18885
Full Name retinoschisin 1
Calculated Molecular Weight 26 kDa
Observed Molecular Weight 26 kDa
GenBank Accession NumberBC141638
Gene Symbol RS1
Gene ID (NCBI) 6247
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

RS1 is also named as XLRS1. RS1 can bind negatively charged membrane lipids, such as phosphatidylserine and phosphoinositides. RS1 is required for normal structure and function of the retina (PMID:19093009). It may play a role in cell-cell adhesion processes in the retina (PMID:27114531). RS1 is high expression in the retina (at protein level) (PMID:10915776, PMID:9326935). It is detected in the inner segment of the photoreceptors, the inner nuclear layer, the inner plexiform layer and the ganglion cell layer. At the macula, it is expressed in both the outer and inner nuclear layers and in the inner plexiform layer (PMID:10915776, PMID:10915776). And RS1 is undetectable in the inner plexiform layers and the inner nuclear layer (PMID:10915776)