ROR2 Monoclonal antibody, PBS Only

ROR2 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67906-1-PBS
Clone No.1A12C5

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse, Rat

Applications

WB, Indirect ELISA

BDB, BDB1, NTRKR2, ROR2

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

67906-1-PBS targets ROR2 in WB, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.

Tested Reactivity Human, Mouse, Rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen ROR2 fusion protein Ag31197 Predict reactive species
Full Name receptor tyrosine kinase-like orphan receptor 2
Calculated Molecular Weight 943 aa, 105 kDa
Observed Molecular Weight105 kDa
GenBank Accession NumberBC130522
Gene Symbol ROR2
Gene ID (NCBI) 4920
RRIDAB_2918662
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ01974
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Tyrosine-protein kinase transmembrane receptor ROR2 belongs to the ROR family of receptor tyrosine kinases (RTKs) (PMID: 12815588). ROR2 is a developmentally regulated protein that has significant expression and roles in a wide variety of tissues during early embryonic development. It was established that ROR2 plays a key role in skeletal and neural organogenesis, as well as in midgut development in the mouse, but then becomes repressed in adult tissues. It may act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PMID: 25614331). Mutations in the ROR2 gene are associated with autosomal recessive Robinow syndrome and autosomal dominant brachydactyly type B (PMID: 12815588).

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