Product Information
28671-1-PBS targets RFC5 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | RFC5 fusion protein Ag29236 Predict reactive species |
Full Name | replication factor C (activator 1) 5, 36.5kDa |
Calculated Molecular Weight | 36 aa, 5 kDa |
GenBank Accession Number | BC001866 |
Gene Symbol | RFC5 |
Gene ID (NCBI) | 5985 |
RRID | AB_2918189 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P40937 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Replication factor C subunit 5 (RFC5), also known as activator 1, can recruit proliferating cell nuclear antigen(PCNA) onto the DNA polymerase S-phase checkpoint complex. In eukaryotes, RFC5 is involved in repairing mismatches, DNA double helix damage, nucleotide excision, and regulating the cell cycle(PMID: 30210909). RFC5 is significantly upregulated in cancer tissues or cells, and its expression is elevated with the cancer progression(PMID: 30214556).