RCAS1 Monoclonal antibody

RCAS1 Monoclonal Antibody for ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Publications

1

CloneNo.

4H8A12

Cat no : 66170-1-Ig

Synonyms

EBAG9, Estrogen receptor-binding fragment-associated gene 9 protein, EBAG 9, EB9, Cancer-associated surface antigen RCAS1

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Validation Data Gallery

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Published Applications

• WB: See 1 publications below
• IF: See 1 publications below

Product Information

66170-1-Ig targets RCAS1 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: mouse
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: RCAS1 fusion protein Ag2905
• Full Name: estrogen receptor binding site associated, antigen, 9
• Calculated Molecular Weight: 213 aa, 24 kDa
• Observed Molecular Weight: 34 kDa
• GenBank Accession Number: BC017729
• Gene Symbol: RCAS1
• Gene ID (NCBI): 9166
• RRID: AB_2881565
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Estrogen receptor-binding fragment-associated antigen 9 (EBAG9) gene was identified as an estrogen-responsive gene. The gene product, receptor-binding cancer antigen expressed on SiSo cells (RCAS1), is associated with aggressive characteristics and poor overall survival for 15 different human malignancies. The correlation between RCAS1 expression and several clinicopathological variables, including tumor size, clinical stage, invasion depth and lymph node metastasis highlights this molecule's clinical significance. Expression of RCAS1 in tumor cells plays an important role in evasion from host immune system resulting tumor progression, invasion and metastasis. Further exploration of RCAS1 biological function will facilitate development of novel therapeutic strategies that target RCAS1.

Publications

Species	Application	Title
mouse	WB,IF	Mol Med Rep; RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation; Authors - Takuya Nishinakagawa