Protein C inhibitor Monoclonal antibody, PBS Only

Protein C inhibitor Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2H6G2

Cat no : 66030-1-PBS

Synonyms

PAI3, PCI, PLANH3, PROCI, Protein C inhibitor, SERPINA5

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Validation Data Gallery

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  WB analysis of human testis using 66030-1-Ig (same clone as 66030-1-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 66030-1-Ig (Protein C inhibitor antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66030-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human testis using 66030-1-Ig (same clone as 66030-1-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 66030-1-Ig (Protein C inhibitor antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66030-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human spleen using 66030-1-Ig (same clone as 66030-1-PBS)

  human spleen tissue were subjected to SDS PAGE followed by western blot with 66030-1-Ig (Protein C inhibitor antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66030-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human spleen using 66030-1-Ig (same clone as 66030-1-PBS)

  human spleen tissue were subjected to SDS PAGE followed by western blot with 66030-1-Ig (Protein C inhibitor antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66030-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 66030-1-Ig (same clone as 66030-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 66030-1-Ig (Protein C inhibitor antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66030-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 66030-1-Ig (same clone as 66030-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 66030-1-Ig (Protein C inhibitor antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66030-1-PBS in a different storage buffer formulation.

• 

  IF Staining of human ovary tumor using 66030-1-Ig (same clone as 66030-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human ovary tumor tissue using Protein C inhibitor antibody (66030-1-Ig, Clone: 2H6G2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66030-1-PBS in a different storage buffer formulation.

• 

  IF Staining of human ovary tumor using 66030-1-Ig (same clone as 66030-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human ovary tumor tissue using Protein C inhibitor antibody (66030-1-Ig, Clone: 2H6G2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66030-1-PBS in a different storage buffer formulation.

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Product Information

66030-1-PBS targets Protein C inhibitor in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG2a
• Class: Monoclonal
• Type: Antibody
• Immunogen: Protein C inhibitor fusion protein Ag18094
• Full Name: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
• Calculated Molecular Weight: 46 kDa
• Observed Molecular Weight: 46 kDa
• GenBank Accession Number: BC008915
• Gene Symbol: SERPINA5
• Gene ID (NCBI): 5104
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

SERPINA5 (also called Protein C Inhibitor, PCI ) is a serpin type of serine protease inhibitor that is found in many tissues and fluids in human, including blood plasma, seminal plasma and urine. PCI found in blood originates from the liver and is capable of inhibiting several serine proteases involved in the regulation of coagulation and fibrinolysis, including activated protein C, thrombin, factor Xa, various kallikreins and plasminogen activators. PCI has been found to have antimicrobial and antitumor properties and thus appears to be a multi-functional protein.