Phospho-STK11/LKB1 (Thr189) Recombinant antibody, PBS Only

Phospho-STK11/LKB1 (Thr189) {ptg:Brand} Recombinant Antibody for WB, IF/ICC, FC (Intra), Indirect ELISA
Cat No. 80127-1-PBS
Clone No.5J9

Host / Isotype

Rabbit / IgG

Reactivity

Human, Mouse

Applications

WB, IF/ICC, FC (Intra), Indirect ELISA

LKB1, STK11, STK11/ LKB1, PJS, Liver kinase B1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

80127-1-PBS targets Phospho-STK11/LKB1 (Thr189) in WB, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with Human, Mouse samples.

Tested Reactivity Human, Mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Peptide Predict reactive species
Full Name serine/threonine kinase 11
Calculated Molecular Weight 49 kDa
Observed Molecular Weight50-55 kDa
GenBank Accession NumberBC007981
Gene Symbol LKB1
Gene ID (NCBI) 6794
RRIDAB_2918867
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ15831
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

STK11(serine/threonine-protein kinase 11) is also named as LKB1, PJS, and belongs to the protein kinase superfamily. It controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. The tumour suppressor protein LKB1 is a serine/threonine kinase that has been causally linked to Peutz-Jeghers syndrome (PJS). Defects in STK11 are a cause of Peutz-Jeghers syndrome (PJS) and defects in STK11 have been associated with testicular germ cell tumor (TGCT) and some sporadic cancers, especially lung cancers.

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