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PSMA2 Monoclonal antibody, PBS Only

PSMA2 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, pig, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2H4A10

Cat no : 68240-1-PBS

Synonyms

HC3, Macropain subunit C3, MU, PMSA2, Proteasome component C3, PSC2, PSC3, PSMA2

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using PSMA2 Monoclonal antibody (68240-1-Ig)

    WB analysis using 68240-1-Ig (same clone as 68240-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68240-1-Ig (PSMA2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68240-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human cervical cancer tissue using PSMA2 Monoclonal antibody (68240-1-Ig)

    IHC staining of human cervical cancer using 68240-1-Ig (same clone as 68240-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 68240-1-Ig (PSMA2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68240-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human cervical cancer tissue using PSMA2 Monoclonal antibody (68240-1-Ig)

    IHC staining of human cervical cancer using 68240-1-Ig (same clone as 68240-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 68240-1-Ig (PSMA2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68240-1-PBS in a different storage buffer formulation.

Product Information

68240-1-PBS targets PSMA2 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse, pig, rat samples.

Tested Reactivity Human, mouse, pig, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen PSMA2 fusion protein Ag5837
Full Name proteasome (prosome, macropain) subunit, alpha type, 2
Calculated Molecular Weight 26 kDa
Observed Molecular Weight 26 kDa
GenBank Accession NumberBC047697
Gene Symbol PSMA2
Gene ID (NCBI) 5683
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

PSMA2 (Proteasome subunit alpha type-2) is the essential subunit that contributes to the complete assembly of 20S proteasome complex, involved in the proteolytic degradation of most intracellular proteins. It is required in spermatogenesis and generation of a subset of MHC class I-presented antigenic peptides(PMID: 34711951, PMID: 27342858). Dysregulation of PSMA2 degradation leads to tumorigenesis including cervical cancer (PMID:33684886).