Product Information
12148-1-PBS targets PRKCSH in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | PRKCSH fusion protein Ag2796 Predict reactive species |
Full Name | protein kinase C substrate 80K-H |
Calculated Molecular Weight | 80 kDa |
Observed Molecular Weight | 80 kDa |
GenBank Accession Number | BC013586 |
Gene Symbol | PRKCSH |
Gene ID (NCBI) | 5589 |
RRID | AB_2253107 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P14314 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
PRKCSH encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum (ER). This protein is an acidic phospho-protein known to be a substrate for protein kinase C. Defects in PRKCSH are a cause of an autosomal dominant polycystic liver disease (PCLD). Glucosidase II is an ER-localized enzyme that contains α and β subunits (Glucosidase IIα and Glucosidase IIβ) which form a defined heterodimeric complex.