Product Information
68606-1-PBS targets PLAGL2 in WB, Indirect ELISA applications and shows reactivity with human, rabbit samples.
Tested Reactivity | human, rabbit |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | PLAGL2 fusion protein Ag30227 Predict reactive species |
Full Name | pleiomorphic adenoma gene-like 2 |
Calculated Molecular Weight | 496 aa, 55 kDa |
Observed Molecular Weight | 50-55 kDa |
GenBank Accession Number | BC023655 |
Gene Symbol | PLAGL2 |
Gene ID (NCBI) | 5326 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q9UPG8 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
PLAGL2, also named KIAA0198, belongs to the krueppel C2H2-type zinc-finger protein family. It shows weak transcriptional activatory activity. PLAGL2, a proto-oncogene, is implicated in a variety of cancers including acute myeloid leukemia (AML), malignant glioma, colon cancer, and lung adenocarcinoma. PLAGL2 can function as a tumor suppressor by initiating cell cycle arrest and apoptosis. The calculated molecular weight of PLAGL2 is 55 kDa, but the SUMO1-modifIed form is 68 kDa (PMID: 30535429).