- Featured Product
- KD/KO Validated
PI3 Kinase p110 Alpha Monoclonal antibody, PBS Only
PI3 Kinase p110 Alpha Monoclonal Antibody for WB, IHC, IF/ICC, FC (Intra), ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
Human, Mouse, Rat, Pig, Rabbit, rabbit
Applications
WB, IHC, IF/ICC, FC (Intra), ELISA
Conjugate
Unconjugated
CloneNo.
1F6A7
Cat no : 67071-1-PBS
Synonyms
Validation Data Gallery
Product Information
67071-1-PBS targets PI3 Kinase p110 Alpha in WB, IHC, IF/ICC, FC (Intra), ELISA applications and shows reactivity with Human, Mouse, Rat, Pig, Rabbit, rabbit samples.
Tested Reactivity | Human, Mouse, Rat, Pig, Rabbit, rabbit |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | PI3 Kinase p110 Alpha fusion protein Ag17392 |
Full Name | phosphoinositide-3-kinase, catalytic, alpha polypeptide |
Calculated Molecular Weight | 1068 aa, 124 kDa |
Observed Molecular Weight | 110 kDa |
GenBank Accession Number | BC113601 |
Gene Symbol | PIK3CA |
Gene ID (NCBI) | 5290 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
PIK3CA belongs to the PI3/PI4-kinase family. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal cancer (CRC). Defects in PIK3CA are associated with breast cancer. Defects in PIK3CA are associated with ovarian cancer. Defects in PIK3CA may underlie hepatocellular carcinoma (HCC). Defects in PIK3CA are a cause of keratosis seborrheic (KERSEB).