Product Information
68783-3-PBS targets PTGDS in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.
| Tested Reactivity | human, mouse, rat, pig, rabbit |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | PTGDS fusion protein Ag34483 Predict reactive species |
| Full Name | prostaglandin D2 synthase 21kDa (brain) |
| Calculated Molecular Weight | 21 kDa |
| Observed Molecular Weight | 28 kDa |
| GenBank Accession Number | BC005939 |
| Gene Symbol | PTGDS |
| Gene ID (NCBI) | 5730 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P41222 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
Glycoprotein prostaglandin D2 synthase (PTGDS), also known as L-PGDS, PGDS, and LPGDS, is a member of the lipocalin superfamily and plays dual roles in prostaglandins metabolism and lipid transport (PMID: 34743203). PTGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PTGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. PTGDS is abundantly expressed in the brain and heart and has also been found in testis, prostate, kidney, spleen and leukocytes. It can be found as a collection of monomeric glycoforms with molecular weights in the 27-34 kDa range (PMID: 32430846).
