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PTGDS Monoclonal antibody, PBS Only

PTGDS Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat, pig, rabbit

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2D6E7

Cat no : 68783-3-PBS

Synonyms

Lipocalin-type prostaglandin-D synthase, Glutathione-independent PGD synthase, EC:5.3.99.2, Cerebrin-28, Beta-trace protein

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using PTGDS Monoclonal antibody (68783-3-Ig)

    WB analysis using 68783-3-Ig (same clone as 68783-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68783-3-Ig (PGDS antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68783-3-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using PTGDS Monoclonal antibody (68783-3-Ig)

    WB analysis using 68783-3-Ig (same clone as 68783-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68783-3-Ig (PGDS antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68783-3-PBS in a different storage buffer formulation.

Product Information

68783-3-PBS targets PTGDS in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.

Tested Reactivity human, mouse, rat, pig, rabbit
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen PTGDS fusion protein Ag34483
Full Name prostaglandin D2 synthase 21kDa (brain)
Calculated Molecular Weight 21 kDa
Observed Molecular Weight 28 kDa
GenBank Accession NumberBC005939
Gene Symbol PTGDS
Gene ID (NCBI) 5730
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Glycoprotein prostaglandin D2 synthase (PTGDS), also known as L-PGDS, PGDS, and LPGDS, is a member of the lipocalin superfamily and plays dual roles in prostaglandins metabolism and lipid transport (PMID: 34743203). PTGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PTGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. PTGDS is abundantly expressed in the brain and heart and has also been found in testis, prostate, kidney, spleen and leukocytes. It can be found as a collection of monomeric glycoforms with molecular weights in the 27-34 kDa range (PMID: 32430846).