Product Information
66309-1-PBS targets PEX5 in WB, IHC, Indirect ELISA applications and shows reactivity with human, pig, rat samples.
Tested Reactivity | human, pig, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | PEX5 fusion protein Ag3268 Predict reactive species |
Full Name | peroxisomal biogenesis factor 5 |
Calculated Molecular Weight | 631 aa, 70 kDa |
Observed Molecular Weight | 70-80 kDa |
GenBank Accession Number | BC010621 |
Gene Symbol | PEX5 |
Gene ID (NCBI) | 5830 |
RRID | AB_2881691 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P50542 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
The peroxisomal targeting signal type1 (PTS1) receptor, PEX5, is one member of peroxins (PEXs) which are proteins required for peroxisome assembly. PEX5 and PEX7 function as receptors that recognize PTS1- and PTS2- containing proteins, respectively, and PEX5 binds PTS1 through its C-terminal 40-kDa tetratricopeptide repeat domain. It is a predominantly cytoplasmic, partly peroxisomal protein that appears to shuttle between these compartments as it mediates the import of PTS1-containing proteins. PEX5 has been reported to interact with PEX10, PEX12, PEX13, and PEX14. Defects in PEX5 are a cause of Zellweger syndrome (ZWS), which is a lethal peroxisome biogenesis disorder.